PZF1/YPR186C Summary Help

Standard Name PZF1 1
Systematic Name YPR186C
Alias TFC2 2
Feature Type ORF, Verified
Description Transcription factor IIIA (TFIIIA); essential DNA binding protein required for transcription of 5S rRNA by RNA polymerase III; not involved in transcription of other RNAP III genes; nine conserved zinc fingers; may also bind 5S rRNA (1, 2, 3, 4)
Name Description Putative Zinc Finger 1
Chromosomal Location
ChrXVI:911022 to 909733 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PZF1 GO evidence and references
  View Computational GO annotations for PZF1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
reduction of function
Resources
23 total interaction(s) for 23 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2

Genetic Interactions
  • Negative Genetic: 18
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 429
Molecular Weight (Da) 50,027
Isoelectric Point (pI) 8.52
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:911022 to 909733 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1290 911022..909733 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006390
References cited on this page View Complete Literature Guide for PZF1
1) Woychik NA and Young RA  (1992) Genes encoding transcription factor IIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 89(9):3999-4003
2) Archambault J, et al.  (1992) The deduced sequence of the transcription factor TFIIIA from Saccharomyces cerevisiae reveals extensive divergence from Xenopus TFIIIA. J Biol Chem 267(5):3282-8
3) Shastry BS  (1996) Transcription factor IIIA (TFIIIA) in the second decade. J Cell Sci 109 ( Pt 3):535-9
4) Wang CK and Weil PA  (1989) Purification and characterization of Saccharomyces cerevisiae transcription factor IIIA. J Biol Chem 264(2):1092-9