PZF1/YPR186C Summary

PZF1 BASIC INFORMATION

Standard Name	PZF1
Systematic Name	YPR186C
Alias	TFC2
Feature Type	ORF, Verified
Description	Transcription factor IIIA (TFIIIA), essential protein with nine C2H2 Zn-fingers, binds the 5S rRNA gene through the zinc finger domain and directs assembly of a multiprotein initiation complex for RNA polymerase III; also binds DNA (1, 2)
Name Description	Putative Zinc Finger

GO Annotations	All PZF1 GO evidence and references
	View Computational GO annotations for PZF1
Molecular Function
Manually curated	DNA binding (IDA) RNA polymerase III transcription factor activity (IPI, ISS)
Biological Process
Manually curated	transcription initiation from RNA polymerase III promoter (IPI, ISS)
Cellular Component
Manually curated	transcription factor complex (IPI)

Mutant Phenotype	All PZF1 Phenotype details and references
Large-scale survey
null	inviable
overexpression	filamentous growth: increased resistance to rapamycin: increased

Interactions	PZF1 All interactions details and references
	18 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1
Genetic Interactions	Phenotypic Enhancement: 17

Sequence Information

ChrXVI:911018 to 909729 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 2004-07-21 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1290	911018..909729	2004-07-21	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000006390

PZF1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for PZF1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PZF1]

1)	Woychik NA and Young RA (1992) Genes encoding transcription factor IIIA and the RNA polymerase common subunit RPB6 are divergently transcribed in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 89(9):3999-4003
2)	Pizzi S, et al. (1999) Domain organization and functional properties of yeast transcription factor IIIA species with different zinc stoichiometries. J Biol Chem 274(4):2539-48

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