PWP1/YLR196W Summary Help

Standard Name PWP1 1
Systematic Name YLR196W
Feature Type ORF, Verified
Description Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily (1, 2)
Name Description Periodic tryptophan (W) Protein 1
Chromosomal Location
ChrXII:543968 to 545698 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PWP1 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
conditional
Large-scale survey
conditional
null
overexpression
reduction of function
Resources
113 total interaction(s) for 91 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 84
  • Affinity Capture-RNA: 2
  • PCA: 15
  • Protein-peptide: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Negative Genetic: 3
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 576
Molecular Weight (Da) 63,803
Isoelectric Point (pI) 4.29
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:543968 to 545698 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1731 543968..545698 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004186
References cited on this page View Complete Literature Guide for PWP1
1) Duronio RJ, et al.  (1992) Comparative analysis of the beta transducin family with identification of several new members including PWP1, a nonessential gene of Saccharomyces cerevisiae that is divergently transcribed from NMT1. Proteins 13(1):41-56
2) Zhang W, et al.  (2004) The functional landscape of mouse gene expression. J Biol 3(5):21