PUS2/YGL063W Summary Help

Standard Name PUS2 1
Systematic Name YGL063W
Feature Type ORF, Verified
Description Mitochondrial tRNA:pseudouridine synthase; acts at positions 27 and 28, but not at position 72; efficiently and rapidly targeted to mitochondria, specifically dedicated to mitochondrial tRNA modification; PUS2 has a paralog, PUS1, that arose from the whole genome duplication (1, 2)
Name Description PseudoUridine Synthase
Chromosomal Location
ChrVII:383654 to 384766 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PUS2 GO evidence and references
  View Computational GO annotations for PUS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Large-scale survey
null
Resources
32 total interaction(s) for 32 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Co-purification: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 22
  • Positive Genetic: 5
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 370
Molecular Weight (Da) 41,891
Isoelectric Point (pI) 8.83
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:383654 to 384766 | ORF Map | GBrowse
This feature contains embedded feature(s): YGL063C-A
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1113 383654..384766 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003031
References cited on this page View Complete Literature Guide for PUS2
1) Behm-Ansmant I, et al.  (2007) The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA:{Psi}27/28-synthase. RNA 13(10):1641-7
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61