PSP1/YDR505C Summary Help

PSP1 BASIC INFORMATION

Standard Name PSP1
Systematic Name YDR505C
Alias GIN5
Feature Type ORF, Verified
Description Asn and gln rich protein of unknown function; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition (1, 2)
Name Description Polymerase SuPpressor 2
GO Annotations All PSP1 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All PSP1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
overexpression
Interactions PSP1 All interactions details and references
28 total interaction(s) for 26 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 4
  • Phenotypic Enhancement: 11
  • Phenotypic Suppression: 5

Sequence Information
ChrIV:1459213 to 1456688 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2526 1459213..1456688 2008-06-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002913

PSP1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PSP1]

1) Akada R, et al.  (1997) Screening and identification of yeast sequences that cause growth inhibition when overexpressed. Mol Gen Genet 254(3):267-74
2) Formosa T and Nittis T  (1998) Suppressors of the temperature sensitivity of DNA polymerase alpha mutations in Saccharomyces cerevisiae. Mol Gen Genet 257(4):461-8