PRY3/YJL078C Summary Help

Standard Name PRY3 1
Systematic Name YJL078C
Feature Type ORF, Verified
Description Cell wall-associated protein involved in export of acetylated sterols; member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); role in mating efficiency; expression of full-length transcript is daughter cell-specific; in response to alpha factor, a short transcript starting at +452 is expressed and the long form is repressed by Ste12p (2, 3, 4)
Name Description Pathogen Related in Yeast 1
Chromosomal Location
ChrX:293981 to 291336 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PRY3 GO evidence and references
  View Computational GO annotations for PRY3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 7 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
overexpression
Resources
20 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 11
  • Positive Genetic: 3
  • Synthetic Growth Defect: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 881
Molecular Weight (Da) 89,151
Isoelectric Point (pI) 4.3
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:293981 to 291336 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2646 293981..291336 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003614
References cited on this page View Complete Literature Guide for PRY3
1) Ku, T. et al.  (1996) Characterization of the PRY Genes: Yeast homologs of the plant PR-1 proteins. Unpublished
2) Colman-Lerner A, et al.  (2001) Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates. Cell 107(6):739-50
3) Bickel KS and Morris DR  (2006) Role of the transcription activator Ste12p as a repressor of PRY3 expression. Mol Cell Biol 26(21):7901-12
4) Choudhary V and Schneiter R  (2012) Pathogen-Related Yeast (PRY) proteins and members of the CAP superfamily are secreted sterol-binding proteins. Proc Natl Acad Sci U S A 109(42):16882-7