PRY1/YJL079C Summary Help

Standard Name PRY1 1
Systematic Name YJL079C
Feature Type ORF, Verified
Description Sterol binding protein involved in the export of acetylated sterols; secreted glycoprotein and member of the CAP protein superfamily (cysteine-rich secretory proteins (CRISP), antigen 5, and pathogenesis related 1 proteins); sterol export function is redundant with that of PRY2; may be involved in detoxification of hydrophobic compounds; PRY1 has a paralog, PRY2, that arose from the whole genome duplication (2, 3)
Name Description Pathogen Related in Yeast 1
Chromosomal Location
ChrX:290774 to 289875 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PRY1 GO evidence and references
  View Computational GO annotations for PRY1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 10 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
unspecified
Resources
28 total interaction(s) for 24 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3

Genetic Interactions
  • Dosage Growth Defect: 2
  • Negative Genetic: 17
  • Phenotypic Enhancement: 2
  • Positive Genetic: 3
  • Synthetic Haploinsufficiency: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 299
Molecular Weight (Da) 30,634
Isoelectric Point (pI) 4.3
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:290774 to 289875 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..900 290774..289875 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003615
References cited on this page View Complete Literature Guide for PRY1
1) Ku, T. et al.  (1996) Characterization of the PRY Genes: Yeast homologs of the plant PR-1 proteins. Unpublished
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
3) Choudhary V and Schneiter R  (2012) Pathogen-Related Yeast (PRY) proteins and members of the CAP superfamily are secreted sterol-binding proteins. Proc Natl Acad Sci U S A 109(42):16882-7