PRP6/YBR055C Summary Help

Standard Name PRP6 1
Systematic Name YBR055C
Alias RNA6 2 , TSM7269 3
Feature Type ORF, Verified
Description Splicing factor; component of the U4/U6-U5 snRNP complex (4)
Name Description Pre-mRNA Processing 1
Chromosomal Location
ChrII:347301 to 344602 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 33 cM
Gene Ontology Annotations All PRP6 GO evidence and references
  View Computational GO annotations for PRP6
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
conditional
null
Large-scale survey
conditional
null
reduction of function
repressible
Resources
188 total interaction(s) for 130 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 133
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Biochemical Activity: 4
  • Co-purification: 4
  • Two-hybrid: 6

Genetic Interactions
  • Negative Genetic: 34
  • Positive Genetic: 1
  • Synthetic Lethality: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 899
Molecular Weight (Da) 104,228
Isoelectric Point (pI) 8.04
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:347301 to 344602 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 33 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2700 347301..344602 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000259
References cited on this page View Complete Literature Guide for PRP6
1) Vijayraghavan U, et al.  (1989) Isolation and characterization of pre-mRNA splicing mutants of Saccharomyces cerevisiae. Genes Dev 3(8):1206-16
2) Hartwell LH, et al.  (1970) Identification of ten genes that control ribosome formation in yeast. Mol Gen Genet 109(1):42-56
3) Hilger F, et al.  (1982) Genetic mapping of arg, cpa, car and tsm genes in Saccharomyces cerevisiae by trisomic analysis. Curr Genet 6(2):93-8
4) Stevens SW and Abelson J  (1999) Purification of the yeast U4/U6.U5 small nuclear ribonucleoprotein particle and identification of its proteins. Proc Natl Acad Sci U S A 96(13):7226-31