PRP40/YKL012W Summary Help

Standard Name PRP40
Systematic Name YKL012W
Feature Type ORF, Verified
Description U1 snRNP protein involved in splicing; interacts with the branchpoint-binding protein during the formation of the second commitment complex (1)
Name Description Pre-mRNA Processing
Chromosomal Location
ChrXI:418310 to 420061 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PRP40 GO evidence and references
  View Computational GO annotations for PRP40
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Large-scale survey
conditional
null
reduction of function
Resources
212 total interaction(s) for 144 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 85
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 6
  • Biochemical Activity: 2
  • Co-purification: 1
  • Protein-peptide: 97
  • Reconstituted Complex: 2
  • Two-hybrid: 10

Genetic Interactions
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 5

Resources
Expression Summary
histogram
Resources
Length (a.a.) 583
Molecular Weight (Da) 69,065
Isoelectric Point (pI) 9.71
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:418310 to 420061 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1752 418310..420061 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001495
References cited on this page View Complete Literature Guide for PRP40
1) Abovich N and Rosbash M  (1997) Cross-intron bridging interactions in the yeast commitment complex are conserved in mammals. Cell 89(3):403-12