PRP28/YDR243C Summary Help

PRP28 BASIC INFORMATION

Standard Name PRP28 1
Systematic Name YDR243C
Feature Type ORF, Verified
Description RNA helicase in the DEAD-box family, involved in RNA isomerization at the 5' splice site (2, 3)
Name Description Pre-mRNA Processing
GO Annotations All PRP28 GO evidence and references
    View Computational GO annotations for PRP28
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All PRP28 Phenotype details and references
Classical genetics
conditional
null
Large-scale survey
null
Interactions PRP28 All interactions details and references
18 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-RNA: 1
  • Protein-RNA: 1
Genetic Interactions
  • Synthetic Lethality: 4
  • Synthetic Rescue: 4
Sequence Information
ChrIV:950281 to 948515 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 144.27 cM
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1767 950281..948515 2008-06-05 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002651

PRP28 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for PRP28

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PRP28]

1) Strauss EJ and Guthrie C  (1991) A cold-sensitive mRNA splicing mutant is a member of the RNA helicase gene family. Genes Dev 5(4):629-41
2) Staley JP and Guthrie C  (1999) An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p. Mol Cell 3(1):55-64
3) de la Cruz J, et al.  (1999) Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 24(5):192-8