Standard Name	PRP11
Systematic Name	YDL043C
Alias	RNA11
Feature Type	ORF, Verified
Description	Subunit of the SF3a splicing factor complex, required for spliceosome assembly (1)
Name Description	Pre-mRNA Processing 2

Chromosomal Location	ChrIV:376480 to 375680 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -17.13 cM

	View Computational GO annotations for PRP11
Molecular Function
Manually curated	RNA binding (IDA)
Biological Process
Manually curated	spliceosomal complex assembly (IDA)
Cellular Component
Manually curated	U2-type prespliceosome (IDA)

Classical genetics
conditional	heat sensitivity: increased
Large-scale survey
conditional	resistance to benomyl: decreased
null	competitive fitness: decreased haploinsufficient inviable resistance to ethanol: decreased
reduction of function	competitive fitness: normal
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	144 total interaction(s) for 101 unique genes/features.
Physical Interactions	Affinity Capture-MS: 68 Affinity Capture-Western: 1 Biochemical Activity: 1 Co-purification: 1 PCA: 1 Reconstituted Complex: 6 Two-hybrid: 25
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 20 Positive Genetic: 14 Synthetic Growth Defect: 2 Synthetic Lethality: 2 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:376480 to 375680 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: -17.13 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..801 376480..375680 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002201