PRE5/YMR314W Summary

PRE5 BASIC INFORMATION

Standard Name	PRE5
Systematic Name	YMR314W
Feature Type	ORF, Verified
Description	Alpha 6 subunit of the 20S proteasome (1)
Name Description	PRoteinase yscE

GO Annotations	All PRE5 GO evidence and references
	View Computational GO annotations for PRE5
Molecular Function
Manually curated	endopeptidase activity (TAS)
Biological Process
Manually curated	ubiquitin-dependent protein catabolic process (TAS)
Cellular Component
Manually curated	proteasome core complex, alpha-subunit complex (IPI, ISS) proteasome storage granule (IDA)

Mutant Phenotype	All PRE5 Phenotype details and references
Large-scale survey
conditional	heat sensitivity: increased
null	inviable
repressible	mitochondrial morphology: abnormal

Interactions	PRE5 All interactions details and references
	141 total interaction(s) for 51 unique genes/features.
Physical Interactions	Affinity Capture-MS: 71 Affinity Capture-RNA: 1 Affinity Capture-Western: 6 Co-purification: 1 Reconstituted Complex: 1 Two-hybrid: 13
Genetic Interactions	Synthetic Growth Defect: 18 Synthetic Lethality: 1 Synthetic Rescue: 29

Sequence Information

ChrXIII:901708 to 902412 | |

Last Update

Coordinates: 2004-02-27 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..705	901708..902412	2004-02-27	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000004931

PRE5 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for PRE5

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PRE5]

1)	Heinemeyer W, et al. (1994) PRE5 and PRE6, the last missing genes encoding 20S proteasome subunits from yeast? Indication for a set of 14 different subunits in the eukaryotic proteasome core. Biochemistry 33(40):12229-37

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