Standard Name	POS5 (see Nomenclature conflict Note)
Systematic Name	YPL188W
Feature Type	ORF, Verified
Description	Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress (1)
Name Description	PerOxide Sensitive

Chromosomal Location	ChrXVI:191406 to 192650 | ORF Map | GBrowse

	View Computational GO annotations for POS5
Molecular Function
Manually curated	NADH kinase activity (IDA)
Biological Process
Manually curated	cellular response to oxidative stress (IMP) NADP biosynthetic process (IDA)
Cellular Component
Manually curated	mitochondrial matrix (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	anaerobic growth: decreased rate NADPH accumulation: decreased resistance to paraquat: decreased resistance to hydrogen peroxide: decreased utilization of carbon source: absent vegetative growth: decreased rate
Large-scale survey
null	UV resistance: decreased proton accumulation: decreased proton accumulation: increased competitive fitness: decreased haploproficient oxidative stress resistance: decreased Fus-Mid-GFP distribution: abnormal resistance to wortmannin: decreased resistance to sirolimus: decreased resistance to hydroxyurea: decreased resistance to cycloheximide: decreased resistance to streptomycin: decreased resistance to (S)-lactic acid: decreased resistance to acetic acid: decreased resistance to methyl methanesulfonate: decreased resistance to elesclomol-Cu: decreased resistance to 4-nitroquinoline N-oxide: decreased respiratory growth: decreased rate respiratory growth: absent utilization of nitrogen source: absent vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	53 total interaction(s) for 45 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 Protein-RNA: 1
Genetic Interactions	Dosage Rescue: 3 Negative Genetic: 14 Positive Genetic: 21 Synthetic Growth Defect: 7 Synthetic Lethality: 5 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:191406 to 192650 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1245 191406..192650 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006109