PLM2/YDR501W Summary Help

Standard Name PLM2 1, 2
Systematic Name YDR501W
Feature Type ORF, Verified
Description Putative transcription factor, contains Forkhead Associated domain; found associated with chromatin; target of SBF transcription factor; induced in response to DNA damaging agents and deletion of telomerase; PLM2 has a paralog, TOS4, that arose from the whole genome duplication (2, 3, 4, 5)
Name Description PLasmid Maintenance 1
Chromosomal Location
ChrIV:1451353 to 1452918 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PLM2 GO evidence and references
  View Computational GO annotations for PLM2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
82 total interaction(s) for 80 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 3
  • PCA: 30

Genetic Interactions
  • Dosage Lethality: 1
  • Negative Genetic: 28
  • Positive Genetic: 16
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 521
Molecular Weight (Da) 58,202
Isoelectric Point (pI) 10
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1451353 to 1452918 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1566 1451353..1452918 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002909
References cited on this page View Complete Literature Guide for PLM2
1) Duffy, K. and A. Cashmore  (1999) PLM2: A novel gene required for the correct partitioning of the 2mu-m plasmid of the yeast Saccharomyces cerevisiae
2) Huang M and Elledge SJ  (2000) The FHA domain, a phosphoamino acid binding domain involved in the DNA damage response pathway. Cold Spring Harb Symp Quant Biol 65():413-21
3) Horak CE, et al.  (2002) Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 16(23):3017-33
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Nautiyal S, et al.  (2002) The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 99(14):9316-21