PIB1/YDR313C Summary Help

Standard Name PIB1 1
Systematic Name YDR313C
Feature Type ORF, Verified
Description RING-type ubiquitin ligase of the endosomal and vacuolar membranes; binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain (1, 2)
Name Description PhosphatidylInositol(3)-phosphate Binding
Chromosomal Location
ChrIV:1090079 to 1089219 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PIB1 GO evidence and references
  View Computational GO annotations for PIB1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
24 total interaction(s) for 20 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 14
  • Phenotypic Enhancement: 1
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 286
Molecular Weight (Da) 32,675
Isoelectric Point (pI) 5.77
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1090079 to 1089219 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..861 1090079..1089219 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002721
References cited on this page View Complete Literature Guide for PIB1
1) Burd CG and Emr SD  (1998) Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains. Mol Cell 2(1):157-62
2) Shin ME, et al.  (2001) FYVE domain targets Pib1p ubiquitin ligase to endosome and vacuolar membranes. J Biol Chem 276(44):41388-93