PHR1/YOR386W Summary Help

Standard Name PHR1 1
Systematic Name YOR386W
Feature Type ORF, Verified
Description DNA photolyase involved in photoreactivation; repairs pyrimidine dimers in the presence of visible light; induced by DNA damage; regulated by transcriptional repressor Rph1p (2, 3, 4)
Name Description PHotoreactivation Repair deficient
Chromosomal Location
ChrXV:1066839 to 1068536 | ORF Map | GBrowse
Gbrowse
Genetic position: 205 cM
Gene Ontology Annotations All PHR1 GO evidence and references
  View Computational GO annotations for PHR1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
unspecified
Large-scale survey
null
overexpression
repressible
unspecified
Resources
15 total interaction(s) for 14 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Biochemical Activity: 1
  • Protein-peptide: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Dosage Growth Defect: 2
  • Dosage Lethality: 1
  • Negative Genetic: 2
  • Positive Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 565
Molecular Weight (Da) 66,273
Isoelectric Point (pI) 9.9
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:1066839 to 1068536 | ORF Map | GBrowse
SGD ORF map
Genetic position: 205 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1698 1066839..1068536 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005913
References cited on this page View Complete Literature Guide for PHR1
1) Link, A. and Olson, M.  (1989) Personal Communication, Mortimer Map Edition 10
2) Green G and MacQuillan AM  (1980) Photorepair of ultraviolet-induced petite mutational damage in Saccharomyces cerevisiae requires the product of the PHR1 gene. J Bacteriol 144(2):826-9
3) Schild D, et al.  (1984) Cloning and mapping of Saccharomyces cerevisiae photoreactivation gene PHR1. Mol Cell Biol 4(9):1864-70
4) Sebastian J and Sancar GB  (1991) A damage-responsive DNA binding protein regulates transcription of the yeast DNA repair gene PHR1. Proc Natl Acad Sci U S A 88(24):11251-5