PHO88/YBR106W Summary Help

Standard Name PHO88
Systematic Name YBR106W
Feature Type ORF, Verified
Description Probable membrane protein; involved in phosphate transport; role in the maturation of secretory proteins; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations (1, 2)
Name Description PHOsphate metabolism
Chromosomal Location
ChrII:452658 to 453224 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PHO88 GO evidence and references
  View Computational GO annotations for PHO88
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 11 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
240 total interaction(s) for 204 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 12
  • Affinity Capture-RNA: 4
  • Co-purification: 1
  • PCA: 140

Genetic Interactions
  • Negative Genetic: 54
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 3
  • Positive Genetic: 14
  • Synthetic Growth Defect: 5
  • Synthetic Lethality: 4
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 188
Molecular Weight (Da) 21,137
Isoelectric Point (pI) 10
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:452658 to 453224 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..567 452658..453224 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000310
References cited on this page View Complete Literature Guide for PHO88
1) Yompakdee C, et al.  (1996) A putative membrane protein, Pho88p, involved in inorganic phosphate transport in Saccharomyces cerevisiae. Mol Gen Genet 251(5):580-90
2) Copic A, et al.  (2009) Genomewide analysis reveals novel pathways affecting endoplasmic reticulum homeostasis, protein modification and quality control. Genetics 182(3):757-69