PHO8/YDR481C Summary Help

PHO8 BASIC INFORMATION

Standard Name PHO8
Systematic Name YDR481C
Feature Type ORF, Verified
Description Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides (1, 2, 3)
Also known as: phoH 4
Name Description PHOsphate metabolism
GO Annotations All PHO8 GO evidence and references
    View Computational GO annotations for PHO8
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All PHO8 Phenotype details and references
Large-scale survey
null
Interactions PHO8 All interactions details and references
10 total interaction(s) for 10 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Co-fractionation: 3
  • Protein-RNA: 1
  • Reconstituted Complex: 1
Genetic Interactions
  • Phenotypic Enhancement: 1
Sequence Information
ChrIV:1420243 to 1418543 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 306 cM
Last Update Coordinates: 2008-06-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1701 1420243..1418543 2008-06-05 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000002889

PHO8 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

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Expression Summary histogram

ADDITIONAL INFORMATION for PHO8

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for PHO8]

1) Donella-Deana A, et al.  (1993) Specific dephosphorylation of phosphopeptides by the yeast alkaline phosphatase encoded by PHO8 gene. Biochim Biophys Acta 1177(2):221-8
2) Kaneko Y, et al.  (1985) Transcriptional and post-transcriptional control of PHO8 expression by PHO regulatory genes in Saccharomyces cerevisiae. Mol Cell Biol 5(1):248-52
3) Klionsky DJ and Emr SD  (1989) Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase. EMBO J 8(8):2241-50
4) Toh-E A, et al.  (1976) A gene controlling the synthesis of non specific alkaline phosphatase in Saccharomyces cerevisiae. Biochim Biophys Acta 428(1):182-92