Standard Name	PHO3
Systematic Name	YBR092C
Feature Type	ORF, Verified
Description	Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin (1, 2, 3, 4, 5) Also known as: phoC 6
Name Description	PHOsphate metabolism

Chromosomal Location	ChrII:429101 to 427698 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 47 cM

	View Computational GO annotations for PHO3
Molecular Function
Manually curated	acid phosphatase activity (IMP)
Biological Process
Manually curated	phosphate-containing compound metabolic process (IDA) thiamine-containing compound metabolic process (IDA)
Cellular Component
Manually curated	cell wall-bounded periplasmic space (IMP)

Classical genetics
null	cell shape: abnormal cell size: increased
Large-scale survey
null	competitive fitness: decreased resistance to glycolaldehyde: decreased viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	36 total interaction(s) for 33 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1
Genetic Interactions	Negative Genetic: 24 Phenotypic Enhancement: 1 Positive Genetic: 10
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:429101 to 427698 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 47 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1404 429101..427698 2011-02-03 1997-01-28
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain T7 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000296