PHO11/YAR071W Summary

PHO11/YAR071W Summary

Standard Name	PHO11 1
Systematic Name	YAR071W
Feature Type	ORF, Verified
Description	One of three repressible acid phosphatases; glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2; PHO11 has a paralog, PHO12, that arose from a segmental duplication (2, 3, 4, 5)
Name Description	PHOsphate metabolism

Chromosomal Location	ChrI:225460 to 226863 \| ORF Map \| GBrowse

	Genetic position: 48 cM

Gene Ontology Annotations All PHO11 GO evidence and references

	View Computational GO annotations for PHO11
Molecular Function
Manually curated	acid phosphatase activity (IDA)
Biological Process
Manually curated	phosphate-containing compound metabolic process (TAS)
Cellular Component
Manually curated	extracellular region (IDA)

Mutant phenotypes All PHO11 Phenotype evidence and references

Large-scale survey
overexpression	vegetative growth: decreased rate
Resources	PROPHECY \| SCMD \| ScreenTroll \| Yeast Fitness Database

interactions All PHO11 Interaction evidence and references

	8 total interaction(s) for 8 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5
Genetic Interactions	Negative Genetic: 3
Resources	BioGRID \| BOND \| BioPIXIE \| CYC2008 (complexes) \| Complexome \| DIP \| DRYGIN \| GeneMANIA \| InterologFinder

Expression Summary


Resources	Expression Summary \| Cell cycle and metabolic oscillation \| Cell cycle transcript profile \| Cyclebase \| Genevestigator \| GermOnline \| SPELL \| YMGV \| YeastFunc

Protein Information All PHO11 Protein evidence and references

Localization	YeastRC \| YPL+ \| YeastGFP
Phosphorylation	PhosphoGRID \| PhosphoPep Database
Structure	GPMDB \| SCOP \| YeastRC
Homologs	Ashbya (AGD) \| CGD Homologs \| CGD Homologs \| Fungal Orthogroups Repository \| P-POD \| PDB Homologs \| PhylomeDB \| YGOB \| YOGY

sequence information

ChrI:225460 to 226863 | |

SGD ORF map

: 48 cM

Last Update

Coordinates: 2011-02-03 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1404	225460..226863	2011-02-03	1996-07-31

Retrieve sequences

Analyze Sequence

S288C only	BLASTP \| ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes \| Six-Frame Translation
S288C vs. other species	Fungal Alignment \| BLASTN vs. fungi \| BLASTP at NCBI \| BLASTP vs. fungi \| Synteny Viewer
S288C vs. other strains	Strain Alignment

Resources

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| Search all NCBI (Entrez) \| UniProtKB

Primary SGDID	S000000094

References cited on this page View Complete Literature Guide for PHO11

1)	Kaback, D. (1989) Personal Communication, Mortimer Map Edition 10
2)	Shnyreva MG, et al. (1996) Biochemical properties and excretion behavior of repressible acid phosphatases with altered subunit composition. Microbiol Res 151(3):291-300
3)	Praetorius-Ibba M, et al. (1997) Homologous recombination partly restores the secretion defect of underglycosylated acid phosphatase in yeast. Curr Genet 32(3):190-6
4)	Rudolph H and Hinnen A (1987) The yeast PHO5 promoter: phosphate-control elements and sequences mediating mRNA start-site selection. Proc Natl Acad Sci U S A 84(5):1340-4
5)	Katju V, et al. (2009) Variation in gene duplicates with low synonymous divergence in Saccharomyces cerevisiae relative to Caenorhabditis elegans. Genome Biol 10(7):R75