PRM15/YMR278W Summary Help

Standard Name PRM15 1
Systematic Name YMR278W
Alias PGM3 2
Feature Type ORF, Verified
Description Phosphoribomutase; catalyzes interconversion of ribose-1-phosphate and ribose-5-phosphate; has some phosphoglucomutase activity but primary activity in vivo is phosphoribomutase; contributes to ribose recycling in the pentose phosphate pathway; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential (2, 3, 4)
Name Description Phospho Ribo Mutase 1
Chromosomal Location
ChrXIII:822763 to 824631 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PRM15 GO evidence and references
  View Computational GO annotations for PRM15
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
6 total interaction(s) for 5 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 622
Molecular Weight (Da) 71,069
Isoelectric Point (pI) 6.22
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:822763 to 824631 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1869 822763..824631 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004891
References cited on this page View Complete Literature Guide for PRM15
1) Xu YF, et al.  (2013) Nucleotide degradation and ribose salvage in yeast. Mol Syst Biol 9():665
2) Tiwari A and Bhat PJ  (2008) Molecular characterization reveals that YMR278w encoded protein is environmental stress response homologue of Saccharomyces cerevisiae PGM2. Biochem Biophys Res Commun 366(2):340-5
3) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4) Walther T, et al.  (2012) The PGM3 gene encodes the major phosphoribomutase in the yeast Saccharomyces cerevisiae. FEBS Lett 586(23):4114-8