PGC1/YPL206C Summary Help

Standard Name PGC1 1
Systematic Name YPL206C
Feature Type ORF, Verified
Description Phosphatidyl Glycerol phospholipase C; regulates the phosphatidylglycerol (PG) content via a phospholipase C-type degradation mechanism; contains glycerophosphodiester phosphodiesterase motifs (2, 3, 4)
Name Description Phosphatidyl Glycerol phospholipase C 1
Chromosomal Location
ChrXVI:163597 to 162632 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PGC1 GO evidence and references
  View Computational GO annotations for PGC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 8 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
13 total interaction(s) for 10 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Negative Genetic: 6
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 321
Molecular Weight (Da) 37,069
Isoelectric Point (pI) 8.93
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:163597 to 162632 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..966 163597..162632 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006127
References cited on this page View Complete Literature Guide for PGC1
1) Simockova M, et al.  (2008) Yeast Pgc1p (YPL206c) Controls the Amount of Phosphatidylglycerol via a Phospholipase C-type Degradation Mechanism. J Biol Chem 283(25):17107-15
2) Beilharz T, et al.  (2003) Bipartite signals mediate subcellular targeting of tail-anchored membrane proteins in Saccharomyces cerevisiae. J Biol Chem 278(10):8219-23
3) Fisher E, et al.  (2005) Glycerophosphocholine-dependent growth requires Gde1p (YPL110c) and Git1p in Saccharomyces cerevisiae. J Biol Chem 280(43):36110-7
4) Fernandez-Murray JP and McMaster CR  (2005) Glycerophosphocholine catabolism as a new route for choline formation for phosphatidylcholine synthesis by the Kennedy pathway. J Biol Chem 280(46):38290-6