PFS1/YHR185C Summary Help

Standard Name PFS1 1
Systematic Name YHR185C
Alias ADY1
Feature Type ORF, Verified
Description Sporulation protein required for prospore membrane formation; required for prospore membrane formation at selected spindle poles; ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation (1)
Name Description Prospore Formation at Spindles 1
Chromosomal Location
ChrVIII:475340 to 474627 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PFS1 GO evidence and references
  View Computational GO annotations for PFS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Large-scale survey
null
overexpression
unspecified
Resources
65 total interaction(s) for 46 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Biochemical Activity: 5
  • Two-hybrid: 8

Genetic Interactions
  • Negative Genetic: 44
  • Phenotypic Enhancement: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 237
Molecular Weight (Da) 27,884
Isoelectric Point (pI) 5.11
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:475340 to 474627 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..714 475340..474627 2005-11-07 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001228
References cited on this page View Complete Literature Guide for PFS1
1) Deng C and Saunders WS  (2001) ADY1, a novel gene required for prospore membrane formation at selected spindle poles in Saccharomyces cerevisiae. Mol Biol Cell 12(9):2646-59