MRM1/YOR201C Summary

MRM1 BASIC INFORMATION

Standard Name	MRM1 1
Systematic Name	YOR201C
Alias	PET56 2
Feature Type	ORF, Verified
Description	Ribose methyltransferase that modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA (2)
Name Description	Mitochondrial rRNA Methyltransferase 1

GO Annotations	All MRM1 GO evidence and references
	View Computational GO annotations for MRM1
Molecular Function
Manually curated	rRNA (guanine-N1-)-methyltransferase activity (IDA)
Biological Process
Manually curated	rRNA modification (IDA)
Cellular Component
Manually curated	mitochondrion (IDA)

Mutant Phenotype	All MRM1 Phenotype details and references
Large-scale survey
null	UV resistance: decreased acid pH resistance: decreased glycogen accumulation: decreased competitive fitness: decreased respiratory growth: decreased rate respiratory growth: absent utilization of carbon source: decreased viable

Interactions	MRM1 All interactions details and references
	28 total interaction(s) for 27 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Two-hybrid: 1
Genetic Interactions	Phenotypic Enhancement: 16 Phenotypic Suppression: 5 Synthetic Growth Defect: 1

Sequence Information

ChrXV:721709 to 720471 | |

Note: this feature is encoded on the Crick strand.

Genetic position: 112 cM

Last Update

Coordinates: 2006-01-05 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1239	721709..720471	2006-01-05	1996-07-31

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005727

MRM1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for MRM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for MRM1]

1)	Pintard L, et al. (2002) MRM2 encodes a novel yeast mitochondrial 21S rRNA methyltransferase. EMBO J 21(5):1139-47
2)	Sirum-Connolly K and Mason TL (1993) Functional requirement of a site-specific ribose methylation in ribosomal RNA. Science 262(5141):1886-9

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