PET191/YJR034W Summary Help

Standard Name PET191
Systematic Name YJR034W
Feature Type ORF, Verified
Description Protein required for assembly of cytochrome c oxidase; exists as an oligomer; described as both an integral mitochondrial inner membrane protein facing the intermembrane space (IMS) and as a soluble IMS protein; contains a twin Cx9C motif; imported into the IMS via the MIA import machinery (1, 2, 3, 4)
Name Description PETite colonies
Chromosomal Location
ChrX:496683 to 497009 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PET191 GO evidence and references
  View Computational GO annotations for PET191
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
dominant negative
null
Large-scale survey
null
Resources
21 total interaction(s) for 21 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • PCA: 3
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 7
  • Phenotypic Enhancement: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 2
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 108
Molecular Weight (Da) 12,394
Isoelectric Point (pI) 7.86
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:496683 to 497009 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..327 496683..497009 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003795
References cited on this page View Complete Literature Guide for PET191
1) McEwen JE, et al.  (1993) Sequence and chromosomal localization of two PET genes required for cytochrome c oxidase assembly in Saccharomyces cerevisiae. Curr Genet 23(1):9-14
2) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54
3) Khalimonchuk O, et al.  (2008) Pet191 is a cytochrome c oxidase assembly factor in Saccharomyces cerevisiae. Eukaryot Cell 7(8):1427-31
4) Voegtle FN, et al.  (2012) Intermembrane space proteome of yeast mitochondria. Mol Cell Proteomics 11(12):1840-52