Standard Name	PET122
Systematic Name	YER153C
Feature Type	ORF, Verified
Description	Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet494p; located in the mitochondrial inner membrane (1)
Name Description	PETite colonies

Chromosomal Location	ChrV:474805 to 474041 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 118 cM

	View Computational GO annotations for PET122
Molecular Function
Manually curated	translation initiation factor activity (IMP)
Biological Process
Manually curated	mitochondrial respiratory chain complex IV biogenesis (IMP) positive regulation of mitochondrial translation (IMP)
Cellular Component
Manually curated	integral to mitochondrial inner membrane (IDA) mitochondrial inner membrane (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	autophagy: decreased colony appearance: abnormal Cox3p accumulation: absent respiratory growth: absent
Large-scale survey
null	glycogen accumulation: decreased polyphosphate accumulation: abnormal glutathione excretion: increased competitive fitness: decreased dessication resistance: decreased resistance to 1,4-dithiothreitol: decreased resistance to sirolimus: decreased resistance to farnesol: decreased respiratory growth: decreased rate respiratory growth: absent stress resistance: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	132 total interaction(s) for 86 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Biochemical Activity: 2 Reconstituted Complex: 1 Two-hybrid: 2
Genetic Interactions	Dosage Lethality: 1 Dosage Rescue: 3 Negative Genetic: 105 Positive Genetic: 1 Synthetic Growth Defect: 2 Synthetic Lethality: 4 Synthetic Rescue: 10
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:474805 to 474041 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 118 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..765 474805..474041 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000955