Standard Name	PET111
Systematic Name	YMR257C
Feature Type	ORF, Verified
Description	Mitochondrial translational activator specific for the COX2 mRNA; located in the mitochondrial inner membrane (1)
Name Description	PETite colonies

Chromosomal Location	ChrXIII:782031 to 779629 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 177 cM

	View Computational GO annotations for PET111
Molecular Function
Manually curated	translation regulator activity (IMP)
Biological Process
Manually curated	mitochondrial respiratory chain complex IV biogenesis (IMP) positive regulation of mitochondrial translation (IMP)
Cellular Component
Manually curated	mitochondrial inner membrane (IDA)
High-throughput	mitochondrion (IDA)

Classical genetics
null	autophagy: decreased petite Cox2p accumulation: absent respiratory growth: absent
overexpression	Cox1p accumulation: decreased respiratory growth: absent
Large-scale survey
null	cell size: decreased proton accumulation: increased proton accumulation: decreased glycogen accumulation: decreased competitive fitness: decreased dessication resistance: decreased haploproficient heat sensitivity: increased resistance to cycloheximide: decreased resistance to ethanol: decreased resistance to methyl methanesulfonate: decreased resistance to amitrole: decreased respiratory growth: absent respiratory growth: decreased rate utilization of carbon source: decreased vegetative growth: decreased rate viable
overexpression	resistance to LY-83583: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	16 total interaction(s) for 11 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 PCA: 2 Two-hybrid: 3
Genetic Interactions	Dosage Rescue: 4 Phenotypic Enhancement: 1 Phenotypic Suppression: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:782031 to 779629 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 177 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2403 782031..779629 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004870