PEF1/YGR058W Summary Help

Standard Name PEF1 1
Systematic Name YGR058W
Feature Type ORF, Verified
Description Penta-EF-hand protein; required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2; binds to Sec31p and modulates COPII coat assembly (1, 2)
Name Description Penta-EF-Hand protein 1
Chromosomal Location
ChrVII:606136 to 607143 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PEF1 GO evidence and references
  View Computational GO annotations for PEF1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
102 total interaction(s) for 79 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 10

Genetic Interactions
  • Negative Genetic: 42
  • Phenotypic Enhancement: 6
  • Phenotypic Suppression: 25
  • Positive Genetic: 14

Resources
Expression Summary
histogram
Resources
Length (a.a.) 335
Molecular Weight (Da) 38,342
Isoelectric Point (pI) 9.67
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:606136 to 607143 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1008 606136..607143 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003290
References cited on this page View Complete Literature Guide for PEF1
1) Vernarecci S, et al.  (2007) The yeast penta-EF protein Pef1p is involved in cation-dependent budding and cell polarization. Mol Microbiol 65(4):1122-38
2) Yoshibori M, et al.  (2012) Involvement of the Penta-EF-Hand Protein Pef1p in the Ca(2+)-Dependent Regulation of COPII Subunit Assembly in Saccharomyces cerevisiae. PLoS One 7(7):e40765