PDR10/YOR328W Summary Help

Standard Name PDR10 1
Systematic Name YOR328W
Feature Type ORF, Verified
Description ATP-binding cassette (ABC) transporter; multidrug transporter involved in the pleiotropic drug resistance network; regulated by Pdr1p and Pdr3p (2, 3, 4, 5)
Name Description Pleiotropic Drug Resistance 5
Chromosomal Location
ChrXV:931803 to 936497 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PDR10 GO evidence and references
  View Computational GO annotations for PDR10
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
unspecified
Resources
50 total interaction(s) for 44 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 2
  • PCA: 26

Genetic Interactions
  • Negative Genetic: 4
  • Phenotypic Enhancement: 2
  • Positive Genetic: 1
  • Synthetic Rescue: 7

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,564
Molecular Weight (Da) 176,459
Isoelectric Point (pI) 7.87
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:931803 to 936497 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..4695 931803..936497 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000005855
References cited on this page View Complete Literature Guide for PDR10
1) Parle, A.G., et al.  (1995) PDR10, a candidate pleiotropic drug resistance locus encoding a new ABC transporter in Saccharomyces cerevisiae. Unpublished
2) Parle-McDermott AG, et al.  (1996) Sequence of 29 kb around the PDR10 locus on the right arm of Saccharomyces cerevisiae chromosome XV: similarity to part of chromosome I. Yeast 12(10B Suppl):999-1004
3) Decottignies A, et al.  (1998) ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p. J Biol Chem 273(20):12612-22
4) Wolfger H, et al.  (1997) The yeast ATP binding cassette (ABC) protein genes PDR10 and PDR15 are novel targets for the Pdr1 and Pdr3 transcriptional regulators. FEBS Lett 418(3):269-74
5) Balzi E and Goffeau A  (1995) Yeast multidrug resistance: the PDR network. J Bioenerg Biomembr 27(1):71-6