PCL9/YDL179W Summary Help

Standard Name PCL9 1
Systematic Name YDL179W
Feature Type ORF, Verified
Description Cyclin; forms a functional kinase complex with Pho85p cyclin-dependent kinase (Cdk), expressed in late M/early G1 phase, activated by Swi5p; PCL9 has a paralog, PCL2, that arose from the whole genome duplication (1, 2, 3, 4)
Name Description Pho85 CycLin 1
Chromosomal Location
ChrIV:138291 to 139205 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PCL9 GO evidence and references
  View Computational GO annotations for PCL9
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Large-scale survey
null
overexpression
Resources
28 total interaction(s) for 22 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 1
  • Negative Genetic: 7
  • Positive Genetic: 2
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 304
Molecular Weight (Da) 34,798
Isoelectric Point (pI) 10.44
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:138291 to 139205 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..915 138291..139205 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002338
References cited on this page View Complete Literature Guide for PCL9
1) Measday V, et al.  (1997) A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase. Mol Cell Biol 17(3):1212-23
2) Tennyson CN, et al.  (1998) A role for the Pcl9-Pho85 cyclin-cdk complex at the M/G1 boundary in Saccharomyces cerevisiae. Mol Microbiol 28(1):69-79
3) Aerne BL, et al.  (1998) Swi5 controls a novel wave of cyclin synthesis in late mitosis. Mol Biol Cell 9(4):945-56
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61