PAN5/YHR063C Summary Help

Standard Name PAN5 1
Systematic Name YHR063C
Feature Type ORF, Verified
Description 2-dehydropantoate 2-reductase; part of the pantothenic acid pathway, structurally homologous to E. coli panE (2)
Name Description PANtothenate biosynthesis 2
Chromosomal Location
ChrVIII:225169 to 224030 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PAN5 GO evidence and references
  View Computational GO annotations for PAN5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Pathways
39 total interaction(s) for 33 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 16
  • Affinity Capture-RNA: 2
  • Biochemical Activity: 1
  • PCA: 1
  • Protein-peptide: 3
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 10
  • Phenotypic Enhancement: 1
  • Positive Genetic: 2
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 379
Molecular Weight (Da) 42,821
Isoelectric Point (pI) 6.61
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:225169 to 224030 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1140 225169..224030 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001105
References cited on this page View Complete Literature Guide for PAN5
1) Patil KR and Nielsen J  (2005) Uncovering transcriptional regulation of metabolism by using metabolic network topology. Proc Natl Acad Sci U S A 102(8):2685-9
2) White WH, et al.  (2001) Saccharomyces cerevisiae is capable of de Novo pantothenic acid biosynthesis involving a novel pathway of beta-alanine production from spermine. J Biol Chem 276(14):10794-800