PAD1/YDR538W Summary Help

Standard Name PAD1 1
Systematic Name YDR538W
Alias POF1
Feature Type ORF, Verified
Description Phenylacrylic acid decarboxylase; confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives; also has mRNA binding activity; homolog of E. coli UbiX (1, 2, 3, 4)
Name Description Phenylacrylic Acid Decarboxylase 1
Chromosomal Location
ChrIV:1510902 to 1511630 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All PAD1 GO evidence and references
  View Computational GO annotations for PAD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
overexpression
unspecified
Large-scale survey
null
Resources
12 total interaction(s) for 12 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-Western: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Negative Genetic: 7
  • Phenotypic Enhancement: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 242
Molecular Weight (Da) 26,733
Isoelectric Point (pI) 10.43
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1510902 to 1511630 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..729 1510902..1511630 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002946
References cited on this page View Complete Literature Guide for PAD1
1) Clausen M, et al.  (1994) PAD1 encodes phenylacrylic acid decarboxylase which confers resistance to cinnamic acid in Saccharomyces cerevisiae. Gene 142(1):107-12
2) Larsson S, et al.  (2001) Effect of overexpression of Saccharomyces cerevisiae Pad1p on the resistance to phenylacrylic acids and lignocellulose hydrolysates under aerobic and oxygen-limited conditions. Appl Microbiol Biotechnol 57(1-2):167-74
3) Gulmezian M, et al.  (2007) The role of UbiX in Escherichia coli coenzyme Q biosynthesis. Arch Biochem Biophys 467(2):144-53
4) Tsvetanova NG, et al.  (2010) Proteome-Wide Search Reveals Unexpected RNA-Binding Proteins in Saccharomyces cerevisiae.LID - e12671 [pii] PLoS One 5(9)