PAC10/YGR078C Summary Help

Standard Name PAC10 1
Systematic Name YGR078C
Alias GIM2 , PFD3 , RKS2
Feature Type ORF, Verified
Description Part of the heteromeric co-chaperone GimC/prefoldin complex; complex promotes efficient protein folding (2)
Name Description Perish in the Absence of Cin8p 1
Chromosomal Location
ChrVII:640371 to 639772 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All PAC10 GO evidence and references
  View Computational GO annotations for PAC10
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 6 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
Resources
596 total interaction(s) for 347 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 29
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 5
  • Biochemical Activity: 3
  • PCA: 4
  • Reconstituted Complex: 3
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 2
  • Negative Genetic: 177
  • Phenotypic Enhancement: 9
  • Phenotypic Suppression: 2
  • Positive Genetic: 65
  • Synthetic Growth Defect: 156
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 126
  • Synthetic Rescue: 10

Resources
Expression Summary
histogram
Resources
Length (a.a.) 199
Molecular Weight (Da) 23,115
Isoelectric Point (pI) 4.61
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:640371 to 639772 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..600 640371..639772 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003310
References cited on this page View Complete Literature Guide for PAC10
1) Geiser JR, et al.  (1997) Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol Biol Cell 8(6):1035-50
2) Siegers K, et al.  (1999) Compartmentation of protein folding in vivo: sequestration of non-native polypeptide by the chaperonin-GimC system. EMBO J 18(1):75-84