Standard Name	PAA1 1
Systematic Name	YDR071C
Feature Type	ORF, Verified
Description	Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also aralkylamines (e.g. tryptamine, phenylethylamine); may be involved in transcription and/or DNA replication (1, 2)
Name Description	PolyAmine Acetyltransferase 1

Chromosomal Location	ChrIV:589402 to 588827 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for PAA1
Molecular Function
Manually curated	aralkylamine N-acetyltransferase activity (IDA) diamine N-acetyltransferase activity (IDA, IMP)
Biological Process
Manually curated	chromatin organization (IMP)
Cellular Component
High-throughput	cytoplasm (IDA)

Classical genetics
null	killer toxin resistance: decreased resistance to Echinocandin B: increased resistance to hydroxyurea: decreased resistance to calcium dichloride: decreased resistance to ferrozine(2-): decreased resistance to cobalt chloride hexahydrate: decreased viable
Large-scale survey
null	anaerobic growth: decreased auxotrophy competitive fitness: decreased dessication resistance: decreased resistance to sirolimus: increased resistance to selenomethionine: increased resistance to wortmannin: normal resistance to edelfosine: decreased stress resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	214 total interaction(s) for 144 unique genes/features.
Physical Interactions	Affinity Capture-MS: 34 Affinity Capture-RNA: 4 Affinity Capture-Western: 4 PCA: 1 Reconstituted Complex: 2 Two-hybrid: 3
Genetic Interactions	Negative Genetic: 140 Phenotypic Suppression: 2 Positive Genetic: 18 Synthetic Growth Defect: 3 Synthetic Lethality: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:589402 to 588827 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..576 589402..588827 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002478