Standard Name	OPT2
Systematic Name	YPR194C
Feature Type	ORF, Verified
Description	Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans; also plays a role in formation of mature vacuoles (1, 2)
Name Description	OligoPeptide Transporter

Chromosomal Location	ChrXVI:926937 to 924304 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for OPT2
Molecular Function
Manually curated	oligopeptide transporter activity (IDA, ISS)
Biological Process
Manually curated	oligopeptide transport (IDA, ISS) vacuole fusion, non-autophagic (IMP)
Cellular Component
Manually curated	integral to plasma membrane (IC)
High-throughput	integral to membrane (ISM)

Classical genetics
null	spermine accumulation: abnormal metal resistance: decreased carboxypeptidase Y secretion: increased replicative lifespan: increased resistance to spermine: decreased resistance to spermidine: decreased resistance to Bleomycin-A5: decreased resistance to hygromycin B: decreased resistance to Calcofluor White: decreased vacuolar morphology: abnormal
Large-scale survey
null	polyphosphate accumulation: abnormal competitive fitness: increased metal resistance: decreased Fus-Mid-GFP distribution: abnormal resistance to cycloheximide: decreased resistance to streptomycin: decreased resistance to sirolimus: decreased resistance to PM02734: decreased resistance to ethanol: decreased resistance to caffeine: decreased resistance to hygromycin B: decreased resistance to spermine: decreased resistance to wortmannin: normal vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	20 total interaction(s) for 18 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 1 PCA: 6 Protein-peptide: 2
Genetic Interactions	Negative Genetic: 9 Synthetic Growth Defect: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:926937 to 924304 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2634 926937..924304 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000006398