ODC2/YOR222W Summary Help

Standard Name ODC2 1
Systematic Name YOR222W
Feature Type ORF, Verified
Description Mitochondrial inner membrane transporter; exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism; ODC2 has a paralog, ODC1, that arose from the whole genome duplication (2, 3)
Name Description OxoDicarboxylate Carrier 2
Gene Product Alias 2-oxodicarboxylate transporter 2
Chromosomal Location
ChrXV:758330 to 759253 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ODC2 GO evidence and references
  View Computational GO annotations for ODC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 6 genes
Resources
Large-scale survey
null
Resources
45 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Dosage Rescue: 2
  • Negative Genetic: 29
  • Positive Genetic: 8
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 307
Molecular Weight (Da) 34,007
Isoelectric Point (pI) 10.52
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:758330 to 759253 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..924 758330..759253 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000005748
References cited on this page View Complete Literature Guide for ODC2
1) Palmieri L, et al.  (2000) Identification and functions of new transporters in yeast mitochondria. Biochim Biophys Acta 1459(2-3):363-9
2) Palmieri L, et al.  (2001) Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate. J Biol Chem 276(3):1916-22
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61