OCA1/YNL099C Summary Help

Standard Name OCA1 1
Systematic Name YNL099C
Feature Type ORF, Verified
Description Putative protein tyrosine phosphatase; required for cell cycle arrest in response to oxidative damage of DNA (1, 2)
Name Description Oxidant-induced Cell-cycle Arrest 1
Chromosomal Location
ChrXIV:439283 to 438567 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All OCA1 GO evidence and references
  View Computational GO annotations for OCA1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 111 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
147 total interaction(s) for 123 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 16
  • Affinity Capture-RNA: 4
  • Reconstituted Complex: 1
  • Two-hybrid: 6

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Negative Genetic: 76
  • Positive Genetic: 37
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 238
Molecular Weight (Da) 27,205
Isoelectric Point (pI) 4.21
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:439283 to 438567 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..717 439283..438567 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005043
References cited on this page View Complete Literature Guide for OCA1
1) Alic N, et al.  (2001) Identification of a Saccharomyces cerevisiae gene that is required for G1 arrest in response to the lipid oxidation product linoleic acid hydroperoxide. Mol Biol Cell 12(6):1801-10
2) Wishart MJ and Dixon JE  (1998) Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains. Trends Biochem Sci 23(8):301-6