OAC1/YKL120W Summary Help

Standard Name OAC1 1
Systematic Name YKL120W
Feature Type ORF, Verified
Description Mitochondrial inner membrane transporter; transports oxaloacetate, sulfate, thiosulfate, and isopropylmalate; member of the mitochondrial carrier family (1, 2)
Name Description OxaloAcetate Carrier 1
Chromosomal Location
ChrXI:217344 to 218318 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All OAC1 GO evidence and references
  View Computational GO annotations for OAC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 10 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
44 total interaction(s) for 42 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 12
  • Affinity Capture-RNA: 1
  • PCA: 6

Genetic Interactions
  • Negative Genetic: 7
  • Phenotypic Enhancement: 1
  • Positive Genetic: 4
  • Synthetic Growth Defect: 6
  • Synthetic Lethality: 6
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 324
Molecular Weight (Da) 35,153
Isoelectric Point (pI) 10.37
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:217344 to 218318 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..975 217344..218318 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000001603
References cited on this page View Complete Literature Guide for OAC1
1) Palmieri L, et al.  (1999) Identification of the yeast mitochondrial transporter for oxaloacetate and sulfate. J Biol Chem 274(32):22184-90
2) Marobbio CM, et al.  (2008) {alpha}-Isopropylmalate, a Leucine Biosynthesis Intermediate in Yeast, Is Transported by the Mitochondrial Oxalacetate Carrier. J Biol Chem 283(42):28445-53