NTO1/YPR031W Summary Help

NTO1 BASIC INFORMATION

Standard Name NTO1 1, 2
Systematic Name YPR031W
Feature Type ORF, Verified
Description Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3 (3, 4)
Name Description NuA Three Orf
GO Annotations All NTO1 GO evidence and references
    View Computational GO annotations for NTO1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All NTO1 Phenotype details and references
Large-scale survey
null
Interactions NTO1 All interactions details and references
  View additional details at BioGRID
56 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 8
  • Affinity Capture-Western: 2
Genetic Interactions
  • Negative Genetic: 34
  • Phenotypic Enhancement: 5
  • Positive Genetic: 6
  • Synthetic Growth Defect: 1
Sequence Information
ChrXVI:631512 to 633758 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-21 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2247 631512..633758 2004-07-21 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000006235

NTO1 RESOURCES

Click on map for expanded view
SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for NTO1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NTO1]

1) Howe, L. and Workman, J.  (2002) personal communication
2) Perry J  (2006) The Epc-N domain: a predicted protein-protein interaction domain found in select chromatin associated proteins. BMC Genomics 7:6
3) Shi X, et al.  (2007) Proteome-wide Analysis in Saccharomyces cerevisiae Identifies Several PHD Fingers as Novel Direct and Selective Binding Modules of Histone H3 Methylated at Either Lysine 4 or Lysine 36. J Biol Chem 282(4):2450-5
4) Taverna SD, et al.  (2006) Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol Cell 24(5):785-96