NTE1/YML059C Summary Help

Standard Name NTE1 1
Systematic Name YML059C
Feature Type ORF, Verified
Description Serine esterase; homolog of human neuropathy target esterase (NTE); Nte1p-mediated phosphatidylcholine turnover influences transcription factor Opi1p localization, affecting transcriptional regulation of phospholipid biosynthesis genes (1, 2)
Name Description Neuropathy Target Esterase 1
Chromosomal Location
ChrXIII:158258 to 153219 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All NTE1 GO evidence and references
  View Computational GO annotations for NTE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Classical genetics
null
overexpression
Large-scale survey
null
unspecified
Resources
29 total interaction(s) for 24 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 1
  • Co-purification: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 9
  • Positive Genetic: 7
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,679
Molecular Weight (Da) 187,131
Isoelectric Point (pI) 8.19
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:158258 to 153219 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..5040 158258..153219 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004524
References cited on this page View Complete Literature Guide for NTE1
1) Murray JP and McMaster CR  (2005) Nte1p-mediated deacylation of phosphatidylcholine functionally interacts with Sec14p. J Biol Chem 280(9):8544-52
2) Fernandez-Murray JP, et al.  (2009) NTE1-encoded phosphatidylcholine phospholipase b regulates transcription of phospholipid biosynthetic genes. J Biol Chem 284(52):36034-46