NSA2/YER126C Summary Help

Standard Name NSA2 1
Systematic Name YER126C
Feature Type ORF, Verified
Description Protein constituent of 66S pre-ribosomal particles; contributes to processing of the 27S pre-rRNA (1, 2, 3)
Name Description Nop Seven Associated 1
Chromosomal Location
ChrV:414179 to 413394 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All NSA2 GO evidence and references
  View Computational GO annotations for NSA2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
repressible
Large-scale survey
null
overexpression
reduction of function
Resources
119 total interaction(s) for 50 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 83
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 18
  • Co-purification: 3
  • PCA: 4
  • Two-hybrid: 5

Genetic Interactions
  • Dosage Rescue: 2
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 261
Molecular Weight (Da) 29,722
Isoelectric Point (pI) 11.04
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:414179 to 413394 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..786 414179..413394 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000928
References cited on this page View Complete Literature Guide for NSA2
1) Harnpicharnchai P, et al.  (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15
2) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27
3) Lebreton A, et al.  (2006) Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs. J Biol Chem 281(37):27099-108