NOP4/YPL043W Summary Help

NOP4 BASIC INFORMATION

Standard Name NOP4
Systematic Name YPL043W
Alias NOP77
Feature Type ORF, Verified
Description Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs) (1, 2, 3)
Name Description NucleOlar Protein 2
GO Annotations All NOP4 GO evidence and references
    View Computational GO annotations for NOP4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All NOP4 Phenotype details and references
Large-scale survey
null
Interactions NOP4 All interactions details and references
126 total interaction(s) for 58 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 121
  • Affinity Capture-Western: 2
  • PCA: 1
Genetic Interactions
  • Synthetic Lethality: 2
Sequence Information
ChrXVI:469936 to 471993 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-21 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2058 469936..471993 2004-07-21 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005964

NOP4 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for NOP4

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NOP4]

1) Sun C and Woolford JL Jr  (1997) The yeast nucleolar protein Nop4p contains four RNA recognition motifs necessary for ribosome biogenesis. J Biol Chem 272(40):25345-52
2) Sun C and Woolford JL Jr  (1994) The yeast NOP4 gene product is an essential nucleolar protein required for pre-rRNA processing and accumulation of 60S ribosomal subunits. EMBO J 13(13):3127-35
3) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27