NOP13/YNL175C Summary Help

Standard Name NOP13 1
Systematic Name YNL175C
Feature Type ORF, Verified
Description Nucleolar protein found in preribosomal complexes; contains an RNA recognition motif (RRM); relative distribution to the nucleolus increases upon DNA replication stress (1, 2, 3)
Name Description NucleOlar Protein 1
Chromosomal Location
ChrXIV:308612 to 307401 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All NOP13 GO evidence and references
  View Computational GO annotations for NOP13
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
91 total interaction(s) for 79 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 73
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1

Genetic Interactions
  • Negative Genetic: 9
  • Phenotypic Enhancement: 1
  • Positive Genetic: 2
  • Synthetic Lethality: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 403
Molecular Weight (Da) 45,609
Isoelectric Point (pI) 9.94
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:308612 to 307401 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1212 308612..307401 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005119
References cited on this page View Complete Literature Guide for NOP13
1) Wu K, et al.  (2001) Nucleolar protein Nop12p participates in synthesis of 25S rRNA in Saccharomyces cerevisiae. Nucleic Acids Res 29(14):2938-49
2) Oeffinger M, et al.  (2007) Comprehensive analysis of diverse ribonucleoprotein complexes. Nat Methods 4(11):951-6
3) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76