NNF2/YGR089W Summary Help

Standard Name NNF2 1
Systematic Name YGR089W
Feature Type ORF, Verified
Description Protein that exhibits physical and genetic interactions with Rpb8p; Rpb8p is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation (1, 2)
Chromosomal Location
ChrVII:656960 to 659770 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NNF2 GO evidence and references
  View Computational GO annotations for NNF2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
243 total interaction(s) for 165 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 3
  • Two-hybrid: 95

Genetic Interactions
  • Negative Genetic: 129
  • Positive Genetic: 11
  • Synthetic Growth Defect: 2
  • Synthetic Haploinsufficiency: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 936
Molecular Weight (Da) 106,465
Isoelectric Point (pI) 8.93
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:656960 to 659770 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2811 656960..659770 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003321
References cited on this page View Complete Literature Guide for NNF2
1) Samanta MP and Liang S  (2003) Predicting protein functions from redundancies in large-scale protein interaction networks. Proc Natl Acad Sci U S A 100(22):12579-83
2) Briand JF, et al.  (2001) Partners of Rpb8p, a small subunit shared by yeast RNA polymerases I, II and III. Mol Cell Biol 21(17):6056-65