| Standard Name | NMT1 |
|---|---|
| Systematic Name | YLR195C |
| Alias | CDC72 1 |
| Feature Type | ORF, Verified |
| Description | N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction (2, 3, 4, 5) |
| Name Description | N-Myristoyl Transferase 5 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
| Genetic position: 142 cM |
Gene Ontology Annotations All NMT1 GO evidence and references
| View Computational GO annotations for NMT1 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All NMT1 Phenotype evidence and references
| Classical genetics | |
|---|---|
| conditional | |
| null | |
| Large-scale survey | |
| null | |
| reduction of function | |
| Resources |
interactions All NMT1 Interaction evidence and references
| 49 total interaction(s) for 46 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All NMT1 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Genetic position: 142 cM | |||||||||||||
| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000004185 |
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References cited on this page View Complete Literature Guide for NMT1
| 1) | Reed SI, et al. (1988) Isolation and characterization of two genes encoding yeast mating pheromone signaling elements: CDC72 and CDC73. Cold Spring Harb Symp Quant Biol 53 Pt 2:621-7 |
| 2) | Knoll LJ, et al. (1992) Analysis of the compartmentalization of myristoyl-CoA:protein N-myristoyltransferase in Saccharomyces cerevisiae. J Biol Chem 267(8):5366-73 |
| 3) | Stone DE, et al. (1991) N-myristoylation is required for function of the pheromone-responsive G alpha protein of yeast: conditional activation of the pheromone response by a temperature-sensitive N-myristoyl transferase. Genes Dev 5(11):1969-81 |
| 4) | Duronio RJ, et al. (1989) Disruption of the yeast N-myristoyl transferase gene causes recessive lethality. Science 243(4892):796-800 |
| 5) | Towler DA, et al. (1987) Amino-terminal processing of proteins by N-myristoylation. Substrate specificity of N-myristoyl transferase. J Biol Chem 262(3):1030-6 |




