NMD5/YJR132W Summary Help

Standard Name NMD5
Systematic Name YJR132W
Alias KAP119 1
Feature Type ORF, Verified
Description Karyopherin; a carrier protein involved in nuclear import of proteins; importin beta homolog (1, 2, 3)
Chromosomal Location
ChrX:669522 to 672668 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NMD5 GO evidence and references
  View Computational GO annotations for NMD5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
null
Resources
83 total interaction(s) for 73 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 8
  • Co-localization: 1
  • Reconstituted Complex: 4
  • Two-hybrid: 4

Genetic Interactions
  • Negative Genetic: 9
  • Phenotypic Suppression: 1
  • Positive Genetic: 34

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,048
Molecular Weight (Da) 119,967
Isoelectric Point (pI) 4.32
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:669522 to 672668 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3147 669522..672668 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003893
References cited on this page View Complete Literature Guide for NMD5
1) Albertini M, et al.  (1998) A novel nuclear import pathway for the transcription factor TFIIS. J Cell Biol 143(6):1447-55
2) Ferrigno P, et al.  (1998) Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. EMBO J 17(19):5606-14
3) Polizotto RS and Cyert MS  (2001) Calcineurin-dependent nuclear import of the transcription factor Crz1p requires Nmd5p. J Cell Biol 154(5):951-60