NGL1/YOL042W Summary Help

Standard Name NGL1 1
Systematic Name YOL042W
Feature Type ORF, Verified
Description Putative endonuclease; has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (2, 3)
Chromosomal Location
ChrXV:249825 to 250916 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NGL1 GO evidence and references
  View Computational GO annotations for NGL1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 52 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
11 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 7
  • Synthetic Growth Defect: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 363
Molecular Weight (Da) 42,398
Isoelectric Point (pI) 8.33
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:249825 to 250916 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1092 249825..250916 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005402
References cited on this page View Complete Literature Guide for NGL1
1) Chen J, et al.  (2002) CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase. EMBO J 21(6):1414-26
2) Faber AW, et al.  (2002) Ngl2p is a Ccr4p-like RNA nuclease essential for the final step in 3'-end processing of 5.8S rRNA in Saccharomyces cerevisiae. RNA 8(9):1095-101
3) Reinders J, et al.  (2006) Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics. J Proteome Res 5(7):1543-54