NEW1/YPL226W Summary Help

Standard Name NEW1 1
Systematic Name YPL226W
Feature Type ORF, Verified
Description ATP binding cassette protein that cosediments with polysomes and is required for biogenesis of the small ribosomal subunit; Asn/Gln-rich rich region supports [NU+] prion formation and susceptibility to [PSI+] prion induction (1, 2, 3, 4)
Name Description Nu+ 1
Chromosomal Location
ChrXVI:121767 to 125357 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NEW1 GO evidence and references
  View Computational GO annotations for NEW1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant phenotypes All NEW1 Phenotype evidence and references
Classical genetics
null
Large-scale survey
null
Resources
interactions All NEW1 Interaction evidence and references
314 total interaction(s) for 242 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 45
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1
  • PCA: 1
  • Reconstituted Complex: 1
Genetic Interactions
  • Negative Genetic: 209
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 2
  • Positive Genetic: 36
  • Synthetic Growth Defect: 15
Resources
Expression Summary
histogram
Resources
Protein Information All NEW1 Protein evidence and references
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:121767 to 125357 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..3591 121767..125357 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006147
References cited on this page View Complete Literature Guide for NEW1
1) Santoso A, et al.  (2000) Molecular basis of a yeast prion species barrier. Cell 100(2):277-88
2) Decottignies A and Goffeau A  (1997) Complete inventory of the yeast ABC proteins. Nat Genet 15(2):137-45
3) Osherovich LZ and Weissman JS  (2001) Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion. Cell 106(2):183-94
4) Li Z, et al.  (2009) Rational extension of the ribosome biogenesis pathway using network-guided genetics. PLoS Biol 7(10):e1000213