NDD1/YOR372C Summary Help

Standard Name NDD1 1
Systematic Name YOR372C
Feature Type ORF, Verified
Description Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes (1)
Name Description Nuclear Division Defective 1
Chromosomal Location
ChrXV:1036471 to 1034807 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All NDD1 GO evidence and references
  View Computational GO annotations for NDD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Targets 107 genes
Regulators 111 genes
Resources
Classical genetics
null
overexpression
repressible
unspecified
Large-scale survey
null
overexpression
repressible
Resources
28 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 4
  • Biochemical Activity: 7
  • Protein-RNA: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 554
Molecular Weight (Da) 60,522
Isoelectric Point (pI) 10.28
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:1036471 to 1034807 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1665 1036471..1034807 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005899
References cited on this page View Complete Literature Guide for NDD1
1) Loy CJ, et al.  (1999) NDD1, a high-dosage suppressor of cdc28-1N, is essential for expression of a subset of late-S-phase-specific genes in Saccharomyces cerevisiae. Mol Cell Biol 19(5):3312-27
2) Harbison CT, et al.  (2004) Transcriptional regulatory code of a eukaryotic genome. Nature 431(7004):99-104