NCP1/YHR042W Summary Help

Standard Name NCP1
Systematic Name YHR042W
Alias CPR1 1
Feature Type ORF, Verified
Description NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated and coordinately regulated with Erg11p (2)
Chromosomal Location
ChrVIII:190543 to 192618 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NCP1 GO evidence and references
  View Computational GO annotations for NCP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 7 genes
Resources
Classical genetics
null
overexpression
repressible
unspecified
Large-scale survey
null
reduction of function
repressible
Resources
75 total interaction(s) for 62 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 21
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Co-purification: 1
  • PCA: 11
  • Reconstituted Complex: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 15
  • Phenotypic Enhancement: 1
  • Positive Genetic: 9
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 10

Resources
Expression Summary
histogram
Resources
Length (a.a.) 691
Molecular Weight (Da) 76,771
Isoelectric Point (pI) 4.89
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:190543 to 192618 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2076 190543..192618 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001084
References cited on this page View Complete Literature Guide for NCP1
1) Daum G, et al.  (1999) Systematic analysis of yeast strains with possible defects in lipid metabolism. Yeast 15(7):601-14
2) Turi TG and Loper JC  (1992) Multiple regulatory elements control expression of the gene encoding the Saccharomyces cerevisiae cytochrome P450, lanosterol 14 alpha-demethylase (ERG11). J Biol Chem 267(3):2046-56