| Standard Name | NAT5 |
|---|---|
| Systematic Name | YOR253W |
| Alias | ARD2 , ROG2 1 , NAA50 2 |
| Feature Type | ORF, Verified |
| Description | Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing (3, 4, 5, 6) |
| Name Description | N-terminal AcetylTransferase |
| Chromosomal Location | |
|---|---|
Gene Ontology Annotations All NAT5 GO evidence and references
| View Computational GO annotations for NAT5 | |
| Molecular Function | |
| Manually curated | |
| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All NAT5 Phenotype evidence and references
| Classical genetics | |
|---|---|
| null | |
| Large-scale survey | |
| null |
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| Resources |
interactions All NAT5 Interaction evidence and references
| 24 total interaction(s) for 20 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All NAT5 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000005779 |
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References cited on this page View Complete Literature Guide for NAT5
| 1) | Andoh T, et al. (2000) Yeast glycogen synthase kinase 3 is involved in protein degradation in cooperation with Bul1, Bul2, and Rsp5. Mol Cell Biol 20(18):6712-20 |
| 2) | Polevoda B, et al. (2009) A synopsis of eukaryotic Nalpha-terminal acetyltransferases: nomenclature, subunits and substrates. BMC Proc 3 Suppl 6:S2 |
| 3) | Park EC and Szostak JW (1992) ARD1 and NAT1 proteins form a complex that has N-terminal acetyltransferase activity. EMBO J 11(6):2087-93 |
| 4) | Mullen JR, et al. (1989) Identification and characterization of genes and mutants for an N-terminal acetyltransferase from yeast. EMBO J 8(7):2067-75 |
| 5) | Polevoda B and Sherman F (2003) Composition and function of the eukaryotic N-terminal acetyltransferase subunits. Biochem Biophys Res Commun 308(1):1-11 |
| 6) | Gautschi M, et al. (2003) The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides. Mol Cell Biol 23(20):7403-14 |




